FES 抗体
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北京 101111
Quick Overview for FES 抗体 (ABIN498416)
抗原
See all FES 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Fes protein. (region surrounding Lys161)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Feline Sarcoma Oncogene (FES) antibody
FES 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 7C7 unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 1-822) antibodyFES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A3-1E5 unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 120-420) antibodyFES 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 613-822) antibodyFES 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 2E3G3 unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 1-822) antibodyFES 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (C-Term) antibodyFES 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 510-770) antibodyFES 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 121-220) antibodyFES 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (N-Term) antibodyFES 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Feline Sarcoma Oncogene (FES) (AA 28-77) antibodyFES 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, Pig, 猴, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FES (Feline Sarcoma Oncogene (FES))
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别名
- C-Fes
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背景
- FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex.Synonyms: FES, FPS, Proto-oncogene c-Fps, Proto-oncogene tyrosine-protein kinase Fes/Fps
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分子量
- approx. 80 kDa
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基因ID
- 2242
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NCBI登录号
- NP_001996
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UniProt
- P07332
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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