TRIM24 抗体
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北京 101111
Quick Overview for TRIM24 抗体 (ABIN498408)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of TIF1alpha protein. (region surrounding Gln1034)
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- TIF1-alpha / TRIM24
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背景
- The protein mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains (a RING, a B box type 1 and a B box type 2) and a coiled coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.Synonyms: RING finger protein 82, RNF82, TIF1, TIF1 alpha, TIF1A, Transcription intermediary factor 1-alpha, Tripartite motif-containing protein 24
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分子量
- approx. 117 kDa
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基因ID
- 8805
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NCBI登录号
- NP_056989
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UniProt
- O15164
抗原
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