MAPK15 抗体
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Quick Overview for MAPK15 抗体 (ABIN498400)
抗原
See all MAPK15 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ERK8 protein. (region surrounding Asp171)
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 32-61), (N-Term) antibody
MAPK15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12573 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-95) antibodyMAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) antibodyMAPK15 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 168CT10-6-6 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) antibodyMAPK15 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 8C6 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-277) antibodyMAPK15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (Tyr877) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-245) antibodyMAPK15 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH 7.2, 0,05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
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别名
- MAPK15
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背景
- The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15
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分子量
- approx. 60 kDa
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基因ID
- 225689
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NCBI登录号
- NP_620590
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UniProt
- Q8TD08
抗原
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