NFYC 抗体
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北京 101111
Quick Overview for NFYC 抗体 (ABIN498393)
抗原
See all NFYC 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of NF-YC protein. (region surrounding Trp85)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NFYC (Nuclear Transcription Factor Y, gamma (NFYC))
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别名
- NFYC
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背景
- The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold Synonyms: Nuclear transcription factor Y subunit gamma, Transactivator HSM-1/2
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分子量
- approx. 50 kDa
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基因ID
- 4802
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NCBI登录号
- NP_055038
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UniProt
- Q13952
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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