Iba1 抗体
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北京 101111
Quick Overview for Iba1 抗体 (ABIN498378)
抗原
See all Iba1 (IBA1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AIF-M1 protein. (region surrounding Tyr85)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (C-Term) antibody
IBA1 适用: 人 WB, IHC, ICC, IF, IHC (p), FACS, IHC (fro), IHC (ff) 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 51-147) antibodyIBA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) antibodyIBA1 适用: 人 WB, IHC, ICC, IP, IF, IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 适用: 大鼠 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (Internal Region) antibodyVerified IBA1 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (C-Term) antibodyVerified IBA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-147) antibodyIBA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 35-102) antibodyIBA1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ionized Calcium-binding Adapter Molecule 1 (IBA1) (AA 1-146) antibodyIBA1 适用: 人 IHC 宿主: 小鼠 Monoclonal AIF1-1909 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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别名
- AIF1
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背景
- Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase 9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
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分子量
- approx. 67 kDa
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基因ID
- 199
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NCBI登录号
- NP_001614
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UniProt
- P55008
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途径
- Smooth Muscle Cell Migration
抗原
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