ARR3 抗体
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Quick Overview for ARR3 抗体 (ABIN498372)
抗原
See all ARR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Arrestin-C protein. (region surrounding Glu374)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibody
Verified ARR3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-359) antibodyARR3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibodyARR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 77-109) antibodyARR3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53545 unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibodyARR3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-359) antibodyARR3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 131-180) antibodyARR3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-260) antibodyARR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
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别名
- Arrestin C / ARR3
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背景
- Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.Synonyms: ARRX, C-ARR, C-Arrestin, CAR, Cone arrestin, Retinal cone arrestin-3, X-arrestin
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分子量
- approx. 40 kDa
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基因ID
- 407
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NCBI登录号
- NP_004303
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UniProt
- P36575
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途径
- Phototransduction, Thromboxane A2 Receptor Signaling
抗原
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