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HTR1F 抗体

The 兔 多克隆 anti-HTR1F antibody is suitable to detect HTR1F in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 IF.
产品编号 ABIN498368
发货至: 中国
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Quick Overview for HTR1F 抗体 (ABIN498368)

抗原

See all HTR1F 抗体
HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

适用

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人, 大鼠, 小鼠

宿主

  • 43
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克隆类型

  • 44
多克隆

标记

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This HTR1F antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody detects endogenous levels of SR-1F protein. (region surrounding Thr126)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunofluorscence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

    别名

    Serotonin Receptor 1F (HTR1F)

    背景

    The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. beta-adrenergic bound to adrenaline activates adenylyl cyclase, while alpha2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the alpha2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1-7 (5HT1-7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

    分子量

    approx. 38 kDa

    基因ID

    3355

    NCBI登录号

    NP_000857

    UniProt

    P30939

    途径

    JAK/STAT Signaling
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