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- 抗原 See all CDC42BPB 抗体
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC42BPB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MRCKbeta protein. (region surrounding Phe1665)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product CDC42BPB Primary Antibody
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anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1580-1679) antibody
CDC42BPB 适用: 人 ELISA, WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1580-1679) antibodyCDC42BPB 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 6G3 unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1580-1679) antibodyCDC42BPB 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1609-1711) antibodyCDC42BPB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (C-Term) antibodyCDC42BPB 适用: 人 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1580-1679) antibodyCDC42BPB 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (C-Term) antibodyCDC42BPB 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (C-Term) antibodyCDC42BPB 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB) (AA 1641-1690) antibodyCDC42BPB 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
- 别名
- CDC42BPB (CDC42BPB 产品)
- 别名
- CDC42BPB antibody, wu:fb98c02 antibody, wu:fc48b05 antibody, wu:fc90d12 antibody, si:dkeyp-93h6.2 antibody, MRCKb antibody, MRCKB antibody, CDC42 binding protein kinase beta antibody, CDC42 binding protein kinase beta (DMPK-like) antibody, CDC42BPB antibody, cdc42bpb antibody, Cdc42bpb antibody
- 背景
- Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.Synonyms: CDC42-binding protein kinase beta, DMPK-like beta, KIAA1124, MRCK beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, Serine/threonine-protein kinase MRCK beta
- 分子量
- approx. 194 kDa
- 基因ID
- 9578
- NCBI登录号
- NP_006026
- UniProt
- Q9Y5S2
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