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- 抗原 See all MED17 抗体
- MED17 (Mediator Complex Subunit 17 (MED17))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of CRSP77 protein. (region surrounding Val171)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product MED17 Primary Antibody
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anti-Mediator Complex Subunit 17 (MED17) (AA 551-651) antibody
MED17 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D4 unconjugated
anti-Mediator Complex Subunit 17 (MED17) antibodyMED17 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibodyMED17 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 411-651) antibodyMED17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 156-205) antibodyMED17 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (Internal Region) antibodyMED17 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 1-300) antibodyMED17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 181-280) antibodyMED17 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (AA 551-651) antibodyMED17 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 17 (MED17) (Internal Region) antibodyMED17 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MED17 (Mediator Complex Subunit 17 (MED17))
- 别名
- MED17 (MED17 产品)
- 别名
- crsp6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, TRAP80 antibody, 77kDa antibody, C330002H14Rik antibody, Crsp6 antibody, Trap80 antibody, mediator of RNA polymerase II transcription subunit 17 antibody, mediator complex subunit 17 antibody, mediator complex subunit 17 L homeolog antibody, AOR_1_2446154 antibody, VDBG_01663 antibody, med17 antibody, med17.L antibody, MED17 antibody, Med17 antibody
- 背景
- In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1. CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits, each having an individual molecular mass ranging from 33 to 200 kDa. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex.Synonyms: ARC77, Activator-recruited cofactor 77 kDa component, CRSP complex subunit 6, CRSP6, Cofactor required for Sp1 transcriptional activation subunit 6, DRIP77, DRIP80, Mediator complex subunit 17, Mediator of RNA polymerase II transcription subunit 17, TRAP80, Thyroid hormone receptor-associated protein complex 80 kDa component, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component
- 分子量
- approx. 73 kDa
- 基因ID
- 9440
- NCBI登录号
- NP_004259
- UniProt
- Q9NVC6
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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