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NPM1 抗体

NPM1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498355
发货至: 中国
  • 抗原 See all NPM1 抗体
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 125
    • 31
    • 1
    • 1
    克隆类型
    • 124
    • 35
    多克隆
    标记
    • 102
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    This NPM1 antibody is un-conjugated
    应用范围
    • 125
    • 62
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Nucleophosmin protein. (region surrounding Glu22)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product NPM1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    别名
    Nucleophosmin (NPM1 产品)
    背景
    The transport of proteins across the nuclear envelope is a selective, multi-step process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. For example, two cytosolic factors critically involved in the recognition and docking process are the karyopherin alpha and karyopherin beta proteins. The karyopherin holoenzyme is a heterodimer of alpha and beta subunits. The nuclear protein B23 (also referred to as nucleophosmin) is involved in ribosomal assembly and rRNA transport. B23 is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.Synonyms: NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin
    分子量
    approx. 36 kDa
    基因ID
    4869
    NCBI登录号
    NP_002511
    UniProt
    P06748
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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