HES6 抗体
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北京 101111
Quick Overview for HES6 抗体 (ABIN498352)
抗原
See all HES6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HES-6 protein. (region surrounding Ala6)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Hairy and Enhancer of Split 6 (HES6) (C-Term) antibody
HES6 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (N-Term) antibodyHES6 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (AA 1-80) antibodyHES6 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (AA 1-224) antibodyHES6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) antibodyHES6 适用: 人 WB 宿主: 小鼠 Monoclonal 3H10 unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) antibodyHES6 适用: 人 WB 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (N-Term) antibodyHES6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (N-Term) antibodyHES6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) (AA 51-100) antibodyHES6 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Hairy and Enhancer of Split 6 (HES6) antibodyHES6 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HES6 (Hairy and Enhancer of Split 6 (HES6))
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别名
- HES6
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背景
- The Drosophila hairy and enhancer of split genes encode basic helix-loophelix (bHLH) transcriptional repressors that function in the notch signaling pathway and control segmentation and neural development during embryogenesis. The mammalian homologues of Drosophila hairy and enhancer of split are the HES gene family members, HES1-6, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis. The HES family members form a complex with TLE, the mammalian homologue of groucho, and this interaction is mediated by the carboxy-terminal WRPW motif of the HES proteins. The HES/TLE complex functions by directly binding to DNA, instead of interfering with activator proteins. Most HES family members, including HES1 and HES5, preferentially bind to the N-box (CACNAG) as opposed to the E-box (CANNTG). HES2 binds to both N- and E-box sites, while HES6 does not bind DNA. Rather, HES6 inhibits HES1 activity, thereby promoting transcription. HES1 and HES2 are expressed in a variety of adult and embryonic tissues.Synonyms: BHLHB41, C-HAIRY1, Class B basic helix-loop-helix protein 41, Hairy and enhancer of split 6, Transcription cofactor HES-6
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分子量
- approx. 30 kDa
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基因ID
- 55502
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NCBI登录号
- NP_061115
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UniProt
- Q96HZ4
抗原
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