GTF2H2 抗体
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北京 101111
Quick Overview for GTF2H2 抗体 (ABIN498339)
抗原
See all GTF2H2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of TFIIH p44 protein. (region surrounding Thr18)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (AA 1-395) antibody
GTF2H2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (AA 1-395) antibodyGTF2H2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (N-Term) antibodyGTF2H2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (C-Term) antibodyGTF2H2 适用: 人, 小鼠, 马, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (N-Term) antibodyGTF2H2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) antibodyGTF2H2 适用: 人 DB 宿主: 小鼠 Monoclonal GTF2F6A10 unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (AA 299-348) antibodyGTF2H2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (AA 36-85) antibodyGTF2H2 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, 兔, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (AA 323-372) antibodyGTF2H2 适用: 人, 小鼠, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) (N-Term) antibodyGTF2H2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
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别名
- GTF2H2 / BTF2P44
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背景
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.Synonyms: BTF2-p44, Basic transcription factor 2 44 kDa subunit, General transcription factor IIH polypeptide 2, General transcription factor IIH subunit 2, TFIIH, TFIIH basal transcription factor complex p44 subunit
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分子量
- approx. 62 kDa
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基因ID
- 2966
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NCBI登录号
- NP_001506
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UniProt
- Q13888
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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