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PFKL 抗体

This 兔 多克隆 antibody specifically detects PFKL in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN498328
发货至: 中国
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Quick Overview for PFKL 抗体 (ABIN498328)

抗原

See all PFKL 抗体
PFKL (Phosphofructokinase, Liver (PFKL))

适用

  • 46
  • 27
  • 20
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 44
  • 5

克隆类型

  • 45
  • 4
多克隆

标记

  • 33
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PFKL antibody is un-conjugated

应用范围

  • 37
  • 20
  • 19
  • 8
  • 6
  • 5
  • 5
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of PFK-C protein. (region surroudning Gln365)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PFKL (Phosphofructokinase, Liver (PFKL))

    别名

    PFKL

    背景

    The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle and liver isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.Synonyms: 6-phosphofructokinase liver, PFK-B, Phosphofructokinase 1, Phosphohexokinase

    分子量

    approx. 85 kDa

    基因ID

    5211

    NCBI登录号

    NP_002617

    UniProt

    P17858

    途径

    Negative Regulation of Hormone Secretion, Warburg Effect
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