CTBP2 抗体
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北京 101111
Quick Overview for CTBP2 抗体 (ABIN498323)
抗原
See all CTBP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This detects endogenous levels of CtBP2 protein. (region surrounding Pro432)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-C-terminal Binding Protein 2 (CTBP2) antibody
CTBP2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) antibodyKD Validated CTBP2 适用: 人 WB, ICC, FACS, IF (p) 宿主: 兔 Monoclonal 23GB5120 unconjugated Recombinant Antibody
anti-C-terminal Binding Protein 2 (CTBP2) (AA 321-445) antibodyCTBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (AA 321-445) antibodyCTBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 7F3E1 unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (C-Term) antibodyCTBP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (AA 1-252) antibodyCTBP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (C-Term) antibodyCTBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (AA 1-513) antibodyCTBP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) antibodyCTBP2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-C-terminal Binding Protein 2 (CTBP2) (AA 429-445), (C-Term) antibodyCTBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
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别名
- CTBP2
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背景
- CtBP1 is a 48 kDa cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding proteins of adenovirus E1A, and they preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation.CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of deltaEF1, a cellular zinc finger-homeodomainprotein, and thereby enhances deltaEF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.Synonyms: C-terminal-binding protein 2
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分子量
- approx. 48 kDa
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基因ID
- 1488
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NCBI登录号
- NP_001077383
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UniProt
- P56545
抗原
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