HNRNPH1 抗体
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北京 101111
Quick Overview for HNRNPH1 抗体 (ABIN498322)
抗原
See all HNRNPH1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of hnRNP H protein. (region surrounding Arg192)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) antibody
KO Validated HNRNPH1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) antibodyKD Validated HNRNPH1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB14105 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (AA 2-449) antibodyHNRNPH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) antibodyHNRNPH1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (AA 48-77), (N-Term) antibodyHNRNPH1 适用: 人 WB 宿主: 兔 Polyclonal RB42336 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (AA 360-409) antibodyHNRNPH1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (C-Term) antibodyHNRNPH1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (C-Term) antibodyHNRNPH1 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (AA 23-52), (N-Term) antibodyHNRNPH1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1) (Internal Region) antibodyHNRNPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))
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别名
- HnRNP-H / HNRNPH1
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背景
- Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport, and also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. hnRNP complexes are the major constituents of the spliceosome and in particular, the hnRNP A1 protein is one of the major premRNA/ mRNA binding proteins and also one of the most abundant proteins in the nucleus. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. Most hnRNP proteins, including hnRNP C1 and C2, contain one or more RNA binding domains and are implicated in the processing of pre-mRNA. hnRNPs F and H are largely related factors that preferentially associate with poly(rG) regions on RNA. Isoforms of these proteins are often generated by alternative processing of the premRNA and by posttranslational modifications such as phosphorylation on serines and threonines and methylation of arginines.Synonyms: HNRPH, HNRPH1, Heterogeneous nuclear ribonucleoprotein H
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分子量
- approx. 50 kDa
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基因ID
- 3187
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NCBI登录号
- NP_005511
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UniProt
- P31943
抗原
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