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HNRNPH1 抗体

HNRNPH1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498322
发货至: 中国
  • 抗原 See all HNRNPH1 抗体
    HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))
    适用
    • 52
    • 20
    • 17
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    克隆类型
    • 52
    多克隆
    标记
    • 24
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HNRNPH1 antibody is un-conjugated
    应用范围
    • 37
    • 28
    • 13
    • 6
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of hnRNP H protein. (region surrounding Arg192)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product HNRNPH1 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HNRNPH1 (Heterogeneous Nuclear Ribonucleoprotein H1 (H) (HNRNPH1))
    别名
    HnRNP-H / HNRNPH1 (HNRNPH1 产品)
    别名
    HNRPH antibody, HNRPH1 antibody, hnRNPH antibody, HNRNPH1 antibody, hnrph antibody, hnrnph antibody, hnrph1 antibody, hnrnph2 antibody, MGC78776 antibody, hnrph2 antibody, MGC80081 antibody, MGC130700 antibody, MGC69543 antibody, AI642080 antibody, E430005G16Rik antibody, Hnrnph antibody, Hnrph1 antibody, Hnrph antibody, zgc:77712 antibody, heterogeneous nuclear ribonucleoprotein H1 antibody, heterogeneous nuclear ribonucleoprotein H2 antibody, heterogeneous nuclear ribonucleoprotein H1 S homeolog antibody, heterogeneous nuclear ribonucleoprotein H1 L homeolog antibody, HNRNPH1 antibody, HNRNPH2 antibody, hnrnph1.S antibody, hnrnph1.L antibody, hnrnph1 antibody, Hnrnph1 antibody
    背景
    Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport, and also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. hnRNP complexes are the major constituents of the spliceosome and in particular, the hnRNP A1 protein is one of the major premRNA/ mRNA binding proteins and also one of the most abundant proteins in the nucleus. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. Most hnRNP proteins, including hnRNP C1 and C2, contain one or more RNA binding domains and are implicated in the processing of pre-mRNA. hnRNPs F and H are largely related factors that preferentially associate with poly(rG) regions on RNA. Isoforms of these proteins are often generated by alternative processing of the premRNA and by posttranslational modifications such as phosphorylation on serines and threonines and methylation of arginines.Synonyms: HNRPH, HNRPH1, Heterogeneous nuclear ribonucleoprotein H
    分子量
    approx. 50 kDa
    基因ID
    3187
    NCBI登录号
    NP_005511
    UniProt
    P31943
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