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- 抗原 See all PFKFB1 抗体
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PFKFB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of PFK-2 liv protein. (region surrounding Glu442)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity-Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product PFKFB1 Primary Antibody
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) antibody
PFKFB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) antibodyPFKFB1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 1-471) antibodyPFKFB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (N-Term) antibodyPFKFB1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) antibodyPFKFB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 1-100) antibodyPFKFB1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) antibodyPFKFB1 适用: 人, 犬, 豚鼠, 马, 斑马鱼, Cow, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 335-384) antibodyPFKFB1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 斑马鱼, Cow, 兔, 猴, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 13-43), (N-Term) antibodyPFKFB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4035 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (AA 259-289) antibodyPFKFB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4038 unconjugated
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- 应用备注
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Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
- 别名
- PFKFB1 (PFKFB1 产品)
- 别名
- zgc:55328 antibody, wu:fi11h10 antibody, PFKFB1 antibody, F6PK antibody, HL2K antibody, PFRX antibody, Pfkfb01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antibody, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antibody, pfkfb1 antibody, PFKFB1 antibody, pfkfb1.S antibody, LOC100475853 antibody, Pfkfb1 antibody
- 背景
- Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2), and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B), and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).Synonyms: 6-biphosphatase 1, 6-phosphofructo-2-kinase/fructose-2, F6PK, PFK-2 liver, PFK/FBPase 1, PFRX
- 分子量
- approx. 52 kDa
- 基因ID
- 5207
- NCBI登录号
- NP_002616
- UniProt
- P16118
- 途径
- Regulation of Carbohydrate Metabolic Process
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