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HNRNPA1 抗体

The 兔 多克隆 anti-HNRNPA1 antibody (ABIN498306) specifically detects HNRNPA1 in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN498306
发货至: 中国
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Quick Overview for HNRNPA1 抗体 (ABIN498306)

抗原

See all HNRNPA1 抗体
HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HNRNPA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of hnRNP A1 protein. (region surrounding Glu85)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 -1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

    别名

    HnRNP Core Protein A1 / HNRNPA1

    背景

    HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.Synonyms: HNRPA1, Helix-destabilizing protein, Heterogeneous nuclear ribonucleoprotein A1, Single-strand RNA-binding protein, hnRNP-A1

    分子量

    approx. 33 kDa

    基因ID

    3178

    NCBI登录号

    NP_002127

    UniProt

    P09651
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