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- 抗原 See all ADRA2A 抗体
- ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADRA2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of AR alpha-2A protein. (region surrounding Arg361)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product ADRA2A Primary Antibody
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anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 385-450) antibody
ADRA2A 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (Internal Region) antibodyADRA2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 240-380) antibodyADRA2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 7-20), (Extracellular), (N-Term) antibodyADRA2A 适用: 大鼠, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (Internal Region) antibodyVerified ADRA2A 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 331-380) antibodyADRA2A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (C-Term) antibodyADRA2A 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 218-374) antibodyADRA2A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 223-256) antibodyADRA2A 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52053 unconjugated
anti-Alpha-2A Adrenergic Receptor (ADRA2A) (AA 118-152) antibodyADRA2A 适用: 人 WB 宿主: 兔 Polyclonal RB53330 unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
- 别名
- alpha-2A Adrenergic Receptor (ADRA2A 产品)
- 别名
- ADRA2A antibody, AW122659 antibody, Adra-2 antibody, Adra-2a antibody, alpha(2A)AR antibody, alpha2-C10 antibody, alpha2A antibody, alpha2A-AR antibody, ADRA2 antibody, ADRA2R antibody, ADRAR antibody, ALPHA2AAR antibody, ZNF32 antibody, CA2-47 antibody, RATRG20 antibody, RG20 antibody, PORA2AR antibody, adrenoceptor alpha 2A antibody, alpha-2A adrenergic receptor-like antibody, adrenergic receptor, alpha 2a antibody, adra2a antibody, ADRA2A antibody, LOC100414445 antibody, Adra2a antibody
- 背景
- This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, apha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.Synonyms: ADRA2A, ADRA2R, ADRAR, Alpha-2A adrenoceptor, Alpha-2A adrenoreceptor
- 分子量
- approx. 48 kDa
- 基因ID
- 150
- NCBI登录号
- NP_000672
- UniProt
- P08913
- 途径
- EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity
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