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LMO4 抗体

The 兔 多克隆 anti-LMO4 antibody (ABIN498291) specifically detects LMO4 in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN498291
发货至: 中国
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Quick Overview for LMO4 抗体 (ABIN498291)

抗原

See all LMO4 抗体
LMO4 (LIM Domain Only 4 (LMO4))

适用

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人, 小鼠, 大鼠

宿主

  • 55
  • 6
  • 1

克隆类型

  • 45
  • 17
多克隆

标记

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  • 2
  • 1
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This LMO4 antibody is un-conjugated

应用范围

  • 50
  • 25
  • 13
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  • 10
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  • 4
  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of LMO4 protein. (region surrounding Glu138)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    PBS, pH 7.2 containing 0.05 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LMO4 (LIM Domain Only 4 (LMO4))

    别名

    LMO4

    背景

    The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2 facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.Synonyms: Breast tumor autoantigen, LIM domain only protein 4, LIM domain transcription factor LMO4, LMO-4, LMO4

    分子量

    approx. 44 kDa

    基因ID

    8543

    NCBI登录号

    NP_006760

    UniProt

    P61968

    途径

    Tube Formation
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