ADK 抗体
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北京 101111
Quick Overview for ADK 抗体 (ABIN498289)
抗原
See all ADK 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ADK protein. (region surrounding Glu6)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Adenosine Kinase (ADK) (AA 1-361) antibody
ADK 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyADK 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyKO Validated ADK 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 200-345) antibodyADK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 165-351) antibodyADK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 18-256) antibodyADK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyADK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 1-345) antibodyADK 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1103CT3-4-3 unconjugated
anti-Adenosine Kinase (ADK) (AA 236-345) antibodyADK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (N-Term) antibodyADK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ADK (Adenosine Kinase (ADK))
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别名
- Adenosine Kinase (AK)
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背景
- Adenosine kinase (ATP:adenosine 5 prime phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin.Synonyms: ADK, Adenosine 5'-phosphotransferase
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分子量
- approx. 40 kDa
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基因ID
- 132
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NCBI登录号
- NP_001114
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UniProt
- P55263
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途径
- Ribonucleoside Biosynthetic Process
抗原
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