Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
AF10 is a putative transcription factor containing a leucine zipper motif. A t (10,11) (p12,q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.Synonyms: myeloid/lymphoid or mixed-lineage leukemia translocated to 10