ADRBK2 抗体
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Quick Overview for ADRBK2 抗体 (ABIN498279)
抗原
See all ADRBK2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GRK 3 protein. (region surrounding Phe391)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 1-300) antibody
ADRBK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (Internal Region) antibodyADRBK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 343-480) antibodyADRBK2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 29-57), (N-Term) antibodyADRBK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21107 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) antibodyADRBK2 适用: 人, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) antibodyADRBK2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (N-Term) antibodyADRBK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (AA 71-120) antibodyADRBK2 适用: 人, 小鼠, 大鼠, 豚鼠, 猴, 兔, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) antibodyADRBK2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) (Internal Region) antibodyADRBK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
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别名
- beta-ARK-2 / ADRBK2
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背景
- Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonistmediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first are the second essenger-regulated kinases such as c-AMP dependent protein kinase A and protein kinase C. The second are the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase, GRK 1, two forms of beta-adrenergic receptor kinase, GRK 2 (betaARK, betaARK1) and GRK 3 (betaARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7.Synonyms: BARK2, Beta-adrenergic receptor kinase 2, G-protein-coupled receptor kinase 3, GRK3
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分子量
- approx. 80 kDa
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基因ID
- 157
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NCBI登录号
- NP_005151
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UniProt
- P35626
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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