CEBPA 抗体
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北京 101111
Quick Overview for CEBPA 抗体 (ABIN498252)
抗原
See all CEBPA 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of C/EBP-α protein. (region surrounding Pro218)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
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别名
- CEBPA
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背景
- C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP α uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growtharrested cells. In the liver, C/EBP α is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP α mRNA and protein, but also the DNA-binding activity of C/EBP α. C/EBP α functions as an important transcription factor that regulates different genes, including Prolactin gene expression.Synonyms: C/EBP alpha, CCAAT/enhancer-binding protein alpha
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分子量
- approx. 30, 43 kDa
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基因ID
- 1050
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NCBI登录号
- NP_004355
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UniProt
- P49715
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途径
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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