CDC37 抗体
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北京 101111
Quick Overview for CDC37 抗体 (ABIN498194)
抗原
See all CDC37 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Cdc37 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) antibody
CDC37 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 241-378) antibodyCDC37 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B3B7 unconjugated
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (pSer13) antibodyCDC37 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (pSer13) antibodyKD Validated CDC37 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3595 unconjugated Recombinant Antibody
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 116-144) antibodyCDC37 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22954 unconjugated
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) antibody (APC)CDC37 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) antibody (Biotin)CDC37 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) antibody (Atto 390)CDC37 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) antibody (Atto 488)CDC37 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) antibody (Atto 594)CDC37 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
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别名
- CDC37
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背景
- Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.Synonyms: CDC37A, Hsp90 chaperone protein kinase-targeting subunit, Hsp90 co-chaperone Cdc37, p50Cdc37
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分子量
- approx. 44 kDa
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基因ID
- 11140
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NCBI登录号
- NP_008996
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UniProt
- Q16543
抗原
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