beta 2 Adrenergic Receptor 抗体
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北京 101111
Quick Overview for beta 2 Adrenergic Receptor 抗体 (ABIN498188)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AR-β2 protein.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 201-300) antibody
ADRB2 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 302-413) antibodyADRB2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5G3B5 unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyVerified ADRB2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 345-373) antibodyADRB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16260 unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation." in: Journal of vascular research, Vol. 54, Issue 5, pp. 259-271, (2017) (PubMed).
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- beta-2 Adrenergic Receptor
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背景
- Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthm,a obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
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分子量
- approx. 47 kDa
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基因ID
- 154
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NCBI登录号
- NP_000015
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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