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beta 2 Adrenergic Receptor 抗体

ADRB2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498188
发货至: 中国
  • 抗原 See all beta 2 Adrenergic Receptor (ADRB2) 抗体
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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    克隆类型
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    多克隆
    标记
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    This beta 2 Adrenergic Receptor antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of AR-β2 protein.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product ADRB2 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Müller, Schwab, Rosenfeld, Antonow-Schlorke, Nathanielsz, Rakers, Schubert, Witte, Rupprecht: "Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation." in: Journal of vascular research, Vol. 54, Issue 5, pp. 259-271, (2017) (PubMed).

  • 抗原
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    别名
    beta-2 Adrenergic Receptor (ADRB2 产品)
    别名
    zgc:162188 antibody, adrb2 antibody, Adrb-2 antibody, Badm antibody, Gpcr7 antibody, ADRB2R antibody, ADRBR antibody, B2AR antibody, BAR antibody, BETA2AR antibody, adrenoceptor beta 2 antibody, adrenoceptor beta 2, surface b antibody, beta2-adrenergic receptor antibody, adrenergic receptor, beta 2 antibody, ADRB2 antibody, adrb2b antibody, LOC100136153 antibody, Adrb2 antibody
    背景
    Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthm,a obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
    分子量
    approx. 47 kDa
    基因ID
    154
    NCBI登录号
    NP_000015
    UniProt
    P07550
    途径
    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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