KSR1 抗体
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Quick Overview for KSR1 抗体 (ABIN498178)
抗原
See all KSR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of KSR protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Kinase Suppressor of Ras 1 (KSR1) antibody
KD Validated KSR1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB6290 unconjugated Recombinant Antibody
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 301-400) antibodyKSR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 404-598) antibodyKSR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 320-420) antibodyKSR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 358-407) antibodyKSR1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 601-750) antibodyKSR1 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (Tyr40) antibodyKSR1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) antibodyKSR1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) (AA 301-400) antibodyKSR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kinase Suppressor of Ras 1 (KSR1) antibodyKSR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KSR1 (Kinase Suppressor of Ras 1 (KSR1))
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别名
- Kinase Suppressor of Ras 1
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背景
- Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFβ-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFβ stimulation.Synonyms: KSR, KSR-1, KSR1
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分子量
- approx. 115 kDa
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基因ID
- 8844
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NCBI登录号
- NP_055053
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UniProt
- Q8IVT5
抗原
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