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TIMP1 抗体

This 兔 多克隆 antibody specifically detects TIMP1 in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN498172
发货至: 中国
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Quick Overview for TIMP1 抗体 (ABIN498172)

抗原

See all TIMP1 抗体
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

适用

  • 206
  • 80
  • 75
  • 30
  • 7
  • 6
  • 6
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  • 2
  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 168
  • 86
  • 10
  • 1
  • 1

克隆类型

  • 146
  • 119
多克隆

标记

  • 110
  • 30
  • 15
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
This TIMP1 antibody is un-conjugated

应用范围

  • 176
  • 98
  • 74
  • 43
  • 39
  • 29
  • 26
  • 25
  • 22
  • 22
  • 11
  • 10
  • 8
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  • 2
  • 1
  • 1
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  • 1
  • 1
Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of TIMP-1 protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    别名

    TIMP1

    背景

    TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases- 1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epitheli,a and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases

    分子量

    approx. 24 kDa

    基因ID

    7076

    NCBI登录号

    NP_003245

    UniProt

    P01033
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