PLD1 抗体
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北京 101111
Quick Overview for PLD1 抗体 (ABIN498163)
抗原
See all PLD1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PLD1 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Phospholipase D1 (PLD1) (AA 965-1074) antibody
PLD1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 10H2 unconjugated
anti-Phospholipase D1 (PLD1) (AA 485-627) antibodyPLD1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D1 (PLD1) (pThr147) antibodyPLD1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D1 (PLD1) (AA 527-576), (pSer561) antibodyPLD1 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PLD1 (Phospholipase D1 (PLD1))
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别名
- Phospholipase D1 / PLD1
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背景
- Activation of phosphatidylcholine-specific phospholipase D (PC-PLD) catalyzes the hydrolysis of phosphatidylcholine (PC) to generate phosphatidic acid (PA). Insulin activates the PLD-dependent hydrolysis of PC in plasma membranes of adipocytes by a mechanism that may involve wortmannin-sensitive phosphatidylinositol 3-kinase. In addition to the transient activation by growth factors stimulation, PC-PLD is constitutively activated in some of the Src- and Ras-transformed cells. PC-PLD is one of the target enzymes of ischemia, its decrease may cause a perturbation of PC hydrolysis and/or disorders of intracellular signal transduction or choline metabolism for acetylcholine formation in the brain.Synonyms: Choline phosphatase 1, PLD-1, Phosphatidylcholine-hydrolyzing phospholipase D1
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基因ID
- 5337
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NCBI登录号
- NP_002653
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UniProt
- Q13393
抗原
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