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PLD1 抗体

PLD1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498163
发货至: 中国
  • 抗原 See all PLD1 抗体
    PLD1 (Phospholipase D1 (PLD1))
    适用
    人, 小鼠, 大鼠
    宿主
    • 33
    • 3
    克隆类型
    • 34
    • 2
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PLD1 antibody is un-conjugated
    应用范围
    • 13
    • 12
    • 4
    • 3
    • 3
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of PLD1 protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product PLD1 Primary Antibody
  • 应用备注
    Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PLD1 (Phospholipase D1 (PLD1))
    别名
    Phospholipase D1 / PLD1 (PLD1 产品)
    别名
    AA536939 antibody, C85393 antibody, Pld1a antibody, Pld1b antibody, Plda antibody, Pldb antibody, phospholipase D1 antibody, Pld1 antibody, PLD1 antibody
    背景
    Activation of phosphatidylcholine-specific phospholipase D (PC-PLD) catalyzes the hydrolysis of phosphatidylcholine (PC) to generate phosphatidic acid (PA). Insulin activates the PLD-dependent hydrolysis of PC in plasma membranes of adipocytes by a mechanism that may involve wortmannin-sensitive phosphatidylinositol 3-kinase. In addition to the transient activation by growth factors stimulation, PC-PLD is constitutively activated in some of the Src- and Ras-transformed cells. PC-PLD is one of the target enzymes of ischemia, its decrease may cause a perturbation of PC hydrolysis and/or disorders of intracellular signal transduction or choline metabolism for acetylcholine formation in the brain.Synonyms: Choline phosphatase 1, PLD-1, Phosphatidylcholine-hydrolyzing phospholipase D1
    基因ID
    5337
    NCBI登录号
    NP_002653
    UniProt
    Q13393
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