HAT1 抗体
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北京 101111
Quick Overview for HAT1 抗体 (ABIN498132)
抗原
See all HAT1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HAT1 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Histone Acetyltransferase 1 (HAT1) antibody
HAT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) antibodyKD Validated HAT1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2090 unconjugated Recombinant Antibody
anti-Histone Acetyltransferase 1 (HAT1) (AA 245-419), (Catalytic Subunit) antibodyHAT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 389-419), (C-Term) antibodyHAT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5769 unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (C-Term) antibodyHAT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 100-338) antibodyHAT1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 331-380) antibodyHAT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 369-419) antibodyHAT1 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone Acetyltransferase 1 (HAT1) (AA 27-58), (N-Term) antibodyHAT1 适用: 人 WB 宿主: 兔 Polyclonal RB5768 unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- HAT1 (Histone Acetyltransferase 1 (HAT1))
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别名
- HAT1
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背景
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.Synonyms: Histone acetyltransferase type B catalytic subunit
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分子量
- approx. 49 kDa
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基因ID
- 8520
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NCBI登录号
- NP_003633
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UniProt
- O14929
抗原
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