CRYAB 抗体
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北京 101111
Quick Overview for CRYAB 抗体 (ABIN498116)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Crystallin-αB protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Crystallin, alpha B (CRYAB) (AA 1-175) antibody
CRYAB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人 WB, IHC, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 6G5 unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal CPTC-CRYAB-1 unconjugated
anti-Crystallin, alpha B (CRYAB) (AA 30-151) antibodyCRYAB 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibody (Atto 488)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 488
anti-Crystallin, alpha B (CRYAB) antibody (Atto 594)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 594
anti-Crystallin, alpha B (CRYAB) antibody (PE)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PE
anti-Crystallin, alpha B (CRYAB) antibody (PerCP)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PerCP
anti-Crystallin, alpha B (CRYAB) antibody (Biotin)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Biotin
anti-Crystallin, alpha B (CRYAB) antibody (FITC)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 FITC
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- alpha-Crystallin B Chain
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背景
- The baculovirus protein p35 inhibits virally-induced apoptosis of invertebrate and mammalian cells and may function to impair the clearing of virally infected cells by the immune system of the host. This is accomplished at least in part by the ability of p35 to block both TNF- and FAS-mediated apoptosis through the inhibition of the ICE family of serine proteases. Two mammalian homologs of baculovirus p35, referred to as inhibitor of apoptosis protein (IAP) 1 and 2, share an amino-terminal baculovirus IAP repeat (BIR) motif and a carboxy-terminal RING finger. Although the c-IAPs do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. Additional IAP family members include ILP (for IAP-like protein) and survivin. ILP inhibits activated caspase-3, leading to the resistance of FASmediated apoptosis. Survivin (also designated TIAP) is expressed during the G2/M phase of the cell cycle and associates with microtubules of the mitotic spindle. Increased caspase-3 activity is detected when a disruption of survivinmicrotubule interactions occurs.Synonyms: Alpha(B)-crystallin, CRYA2, CRYAB, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component
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分子量
- approx. 26 kDa
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基因ID
- 1410
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NCBI登录号
- NP_001876
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UniProt
- P02511
抗原
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