CRYAB 抗体
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北京 101111
Quick Overview for CRYAB 抗体 (ABIN498115)
抗原
See all CRYAB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PP1α protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Crystallin, alpha B (CRYAB) (AA 1-175) antibody
CRYAB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人 WB, IHC, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 6G5 unconjugated
anti-Crystallin, alpha B (CRYAB) antibodyCRYAB 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal CPTC-CRYAB-1 unconjugated
anti-Crystallin, alpha B (CRYAB) (AA 30-151) antibodyCRYAB 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha B (CRYAB) antibody (Atto 488)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 488
anti-Crystallin, alpha B (CRYAB) antibody (Atto 594)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Atto 594
anti-Crystallin, alpha B (CRYAB) antibody (PE)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PE
anti-Crystallin, alpha B (CRYAB) antibody (PerCP)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 PerCP
anti-Crystallin, alpha B (CRYAB) antibody (Biotin)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 Biotin
anti-Crystallin, alpha B (CRYAB) antibody (FITC)CRYAB 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3A10-C9 FITC
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CRYAB (Crystallin, alpha B (CRYAB))
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别名
- alpha-Crystallin B Chain
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背景
- In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP1 family is comprised of subfamily members PP1α, PP1β and PP1γ, which are 37 kDa MgATP-dependent enzymes. PP1 inactivity is maintained through its association with the 16-18 kDa inhibitory protein NIPP-1 (nuclear inhibitor of PP1). Phosphorylation of NIPP-1 by cAMP-PK or casein kinase II results in the release of active PP1.Synonyms: Alpha(B)-crystallin, CRYA2, CRYAB, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component
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分子量
- approx. 26 kDa
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基因ID
- 1410
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NCBI登录号
- NP_001876
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UniProt
- P02511
抗原
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