PBX1 抗体 (Internal Region)
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Quick Overview for PBX1 抗体 (Internal Region) (ABIN498074)
抗原
See all PBX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-ATNVSAHGSQ ANSPS
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide from the internal region of the protein sequence according to NP_002576.1. Genename: PBX1
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anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibody
PBX1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4A2 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 315-430) antibodyPBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Internal Region) antibodyVerified PBX1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 311-403) antibodyPBX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (Center) antibodyPBX1 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (N-Term) antibodyPBX1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 45 kDa in lysates of cell line K562.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine (Dog). Add. Information: Calculated Molecular Weight: 46.5 kDa according to NP_002576.1 -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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别名
- PBX1
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背景
- This nonactivating protein which could be a repressor, binds the sequence 5'-ATCAATCAA-3'. It is converted into a potent transcriptional activator by the (1,19) translocation. PBX1 May have a role in steroidogenesis and subsequently sexual development and differentiation, and is expressed in all tissues except in cells of the B and T lineage. PBX1 is involved in a form of pre-B-cell acute lymphoblastic leukemia (B-ALL) (25 % of human pediatric cases) through a chromosomal translocation t(1,19)(q23,p13.3) which involves PBX1 and E2A genes. E2A-PBX1 transforms cells by constitutively activating transcription of genes regulated by PBX1 or by other members of the PBX protein family. PBX1 belongs to the TALE/PBX homeobox family, and contains 1 homeobox domain.Synonyms: Homeobox protein PBX1, Homeobox protein PRL, Pre-B-cell leukemia transcription factor 1
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基因ID
- 5087
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NCBI登录号
- NP_002576
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UniProt
- P40424
抗原
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