TDGF1 抗体 (Internal Region)
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北京 101111
Quick Overview for TDGF1 抗体 (Internal Region) (ABIN498045)
抗原
See all TDGF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- YGRNCEHDVR KEN
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特异性
- Recognizes CRIPTO
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_003203.1. Genename: TDGF1
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anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 1-188) antibody
TDGF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 37-70), (N-Term) antibodyTDGF1 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB51515 unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (Internal Region) antibodyTDGF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 18-48), (N-Term) antibodyTDGF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3957 unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 1-188) antibodyTDGF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (Internal Region) antibodyVerified TDGF1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 35-188) antibodyTDGF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) antibodyTDGF1 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibodyTDGF1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Peptide ELISA: Detection Limit: 1/128000. Western blot: Preliminary experiments in Human Umbilical Cord lysates and in lysates ofcell lines HEK293 and NIH3T3 gave no specific signal but low background (at antibodyconcentration up to 2 μg/mL). Immunohistochemistry: 3-5 μg/mLIn paraffin embedded Human Placenta shows stainng assocated with nuclei in sometrophoblasts and weak cytoplasm staining in cytotrophoblasts.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C.
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- TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
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别名
- TDGF1 / CRIPTO
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背景
- Human Cripto-1 (CR-1), also known as Teratocarcinoma-derived growth factor 1 (TDGF1), is a member of the epidermal growth factor (EGF)-GFC family and has been implicated in both embryogenesis and carcinogenesis. During early vertebrate development, CR-1 functions as a co-receptor for Nodal, a transforming growth factor beta (TGFbeta) family member, and is essential for mesoderm and endoderm formation and anterior-posterior and left-right axis establishment. In adult tissues, CR-1 is expressed at a low level in all stages of mammary gland development, and expression increases during pregnancy and lactation. Over-expression of CR-1 in mouse mammary epithelial cells leads to their transformation in vitro, and when injected in mammary glands, CR-1 produces ductal hyperplasias.Synonyms: CRGF, Cripto-1 growth factor, Epidermal growth factor-like cripto protein CR1, Teratocarcinoma-derived growth factor 1
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基因ID
- 6997
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NCBI登录号
- NP_003203
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UniProt
- P13385
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途径
- EGFR Signaling Pathway
抗原
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