GOPC 抗体 (C-Term)
Quick Overview for GOPC 抗体 (C-Term) (ABIN497983)
抗原
See all GOPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Recognizes PIST (C-term).
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- PIST antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human PIST
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亚型
- IgG
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anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (AA 203-462) antibody
GOPC 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) antibodyGOPC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (AA 361-390), (C-Term) antibodyGOPC 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB13073 unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) antibodyGOPC 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (C-Term) antibodyGOPC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (C-Term) antibodyVerified GOPC 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (AA 251-300) antibodyGOPC 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (AA 35-84) antibodyGOPC 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼, 猴, Pig, 小鸡, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (AA 195-454) antibodyGOPC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC) (N-Term) antibodyGOPC 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: PIST antibody can be used for the detection of PIST at 1-2 μg/mL. Positive Control: Rat Colon Cell Lysate. Immunohistochemistry on paraffin sections. Positive Control: Rat Colon Cell Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
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- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
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别名
- GOPC / PIST
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6 (4-6). Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1 (6).Synonyms: CAL, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi-associated PDZ and coiled-coil motif-containing protein, PDZ protein interacting specifically with TC10
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基因ID
- 57120
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NCBI登录号
- NP_001017408
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UniProt
- Q9HD26
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途径
- Maintenance of Protein Location, Asymmetric Protein Localization
抗原
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