SYNPO 抗体 (N-Term)
Quick Overview for SYNPO 抗体 (N-Term) (ABIN4956542)
抗原
See all SYNPO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠
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免疫原
- Synthetic peptides (mouse internal N-terminal sequence)
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anti-Synaptopodin (SYNPO) (AA 331-452), (Isoform 2) antibody
SYNPO 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin (SYNPO) (AA 97-300) antibodySYNPO 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin (SYNPO) (AA 331-452), (Isoform 2) antibodySYNPO 适用: 小鼠, 大鼠 IHC, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-Synaptopodin (SYNPO) (AA 601-700) antibodySYNPO 适用: 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin (SYNPO) (AA 601-700) antibody (FITC)SYNPO 适用: 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal FITC
anti-Synaptopodin (SYNPO) (C-Term) antibodySYNPO 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin (SYNPO) (AA 1-260) antibodySYNPO 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Dilution for IHC: 1:50, for WB 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- serum
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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- SYNPO (Synaptopodin (SYNPO))
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别名
- synaptopodin
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背景
- The antibody reacts specifically with synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin. Synaptopodin belongs to actin-binding proteins, it has first been localized in podocytes and a subset of telencephalic postsynaptic densities. In human tissue synaptopodin has a molecular weight of 73.7 kD and pI of 9.38 (calculated from sequence data), in mouse the corresponding data are 74 kD, pI 9.27. In SDS-PAGE the antigen appears as 100 kD polypeptide in brain and 110 kD polypeptide in kidney (attributed to post-translational modifications). In Western blot analysis the antibody also reacts with a 44 kD degradation fragment of synaptopodin. 1. The antibody recognizes differentiated podocytes (glomerular visceral epithelial cells) in vivo and in vitro weaker additional reaction with arterial endothelial cells), co-localization with alpha-actinin. 2. Reacts with a subset of exclusively telencephalic synapses. Differentiation-dependent expression during postnatal maturation of murine brain. Differentiation-depen dent expression in cultured hippocampal neurons.
抗原
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