ZAK 抗体 (AA 271-300)
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Quick Overview for ZAK 抗体 (AA 271-300) (ABIN3032751)
抗原
See all ZAK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-300
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Purified
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免疫原
- A portion of amino acids 271-300 from the human protein was used as the immunogen for this ZAK antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ZAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ZAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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别名
- ZAK (MLKLAK)
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背景
- ZAK/MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
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UniProt
- Q9NYL2
抗原
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