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VASP 抗体 (AA 267-296)

The 兔 多克隆 anti-VASP antibody (ABIN3029586) specifically detects VASP in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN3029586
发货至: 中国
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Quick Overview for VASP 抗体 (AA 267-296) (ABIN3029586)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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宿主

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克隆类型

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多克隆

标记

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This VASP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 267-296

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 267-296 from the human protein was used as the immunogen for this VASP antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the VASP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the VASP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    VASP

    背景

    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

    UniProt

    P50552

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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