UBE2I 抗体 (AA 1-30)
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- 抗原 See all UBE2I 抗体
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
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抗原表位
- AA 1-30
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2I antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Chicken, Zebrafish, Xenopus
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this UBC9 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UBE2I Primary Antibody
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- 应用备注
- Titration of the UBC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the UBC9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- 别名
- UBC9 (UBE2I 产品)
- 背景
- UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.
- UniProt
- P63279
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
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