TSG101 抗体 (AA 340-370)
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北京 101111
Quick Overview for TSG101 抗体 (AA 340-370) (ABIN3029403)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-370
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 340-370 from the human protein was used as the immunogen for this TSG101 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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别名
- TSG101
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背景
- TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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UniProt
- Q99816
抗原
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