TRAF4 抗体 (AA 427-455)
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Quick Overview for TRAF4 抗体 (AA 427-455) (ABIN3029152)
抗原
See all TRAF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 427-455
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 427-455 from the human protein was used as the immunogen for this TRAF4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TRAF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
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别名
- TRAF4
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背景
- This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
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UniProt
- Q9BUZ4
抗原
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