TOR2A 抗体 (AA 194-221)
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Quick Overview for TOR2A 抗体 (AA 194-221) (ABIN3029188)
抗原
See all TOR2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 194-221
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 194-221 from the human protein was used as the immunogen for this TOR2A antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TOR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TOR2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TOR2A (Torsin Family 2, Member A (TOR2A))
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别名
- TOR2A
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背景
- Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
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UniProt
- Q5JU69
抗原
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