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TXN 抗体 (AA 1-30)

This anti-TXN antibody is a 兔 多克隆 antibody detecting TXN in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3029119
发货至: 中国

Quick Overview for TXN 抗体 (AA 1-30) (ABIN3029119)

抗原

See all TXN 抗体
TXN (Thioredoxin (TXN))

适用

  • 105
  • 39
  • 30
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 103
  • 48

克隆类型

  • 84
  • 67
多克隆

标记

  • 90
  • 19
  • 15
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This TXN antibody is un-conjugated

应用范围

  • 114
  • 78
  • 63
  • 44
  • 35
  • 18
  • 16
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 39
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-30

    纯化方法

    Purified

    免疫原

    A portion of amino acids 1-30 from the human protein was used as the immunogen for this Thioredoxin antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Thioredoxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Thioredoxin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TXN (Thioredoxin (TXN))

    别名

    Thioredoxin

    背景

    Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    UniProt

    P10599

    途径

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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