SUZ12 抗体 (AA 559-588)
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Quick Overview for SUZ12 抗体 (AA 559-588) (ABIN3029056)
抗原
See all SUZ12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 559-588
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SUZ12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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别名
- SUZ12
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背景
- Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
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UniProt
- Q15022
抗原
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