SUV39H2 抗体 (AA 360-390)
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Quick Overview for SUV39H2 抗体 (AA 360-390) (ABIN3029054)
抗原
See all SUV39H2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 360-390
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交叉反应 (详细)
- Expected species reactivity: Primate
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纯化方法
- Purified
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免疫原
- A portion of amino acids 360-390 from the human protein was used as the immunogen for this SUV39H2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the SUV39H2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SUV39H2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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别名
- SUV39H2
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背景
- The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59 % identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
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UniProt
- Q9H5I1
抗原
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