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SUV39H2 抗体 (AA 367-395)

SUV39H2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029053
发货至: 中国
  • 抗原 See all SUV39H2 抗体
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 367-395
    适用
    • 59
    • 26
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 57
    • 2
    • 1
    克隆类型
    • 52
    • 8
    多克隆
    标记
    • 31
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SUV39H2 antibody is un-conjugated
    应用范围
    • 44
    • 32
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Expected species reactivity: Mouse, Primate
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 367-395 from the human protein was used as the immunogen for this SUV39H2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SUV39H2 Primary Antibody
  • 应用备注
    Titration of the SUV39H2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SUV39H2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    别名
    SUV39H2 (KTM1B) (SUV39H2 产品)
    背景
    Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.
    UniProt
    Q9H5I1
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