SUMO2/3 抗体 (AA 49-81)
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北京 101111
Quick Overview for SUMO2/3 抗体 (AA 49-81) (ABIN3032650)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 49-81
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交叉反应 (详细)
- Expected species reactivity: Bovine, Chicken, Hamster, Pig, Primate, Rat, Xenopus, Zebrafish
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纯化方法
- Purified
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免疫原
- A portion of amino acids 49-81 from human SUMO3 was used as the immunogen for this SUMO2/3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the SUMO2/3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25-100,Western blot: 1:1000,IHC (FFPE): 1:50-100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SUMO2/3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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别名
- SUMO2/3
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背景
- SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
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UniProt
- P55854
抗原
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