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SUMO2 抗体

This anti-SUMO2 antibody is a 小鼠 单克隆 antibody detecting SUMO2 in WB, ELISA 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN3032647
发货至: 中国

Quick Overview for SUMO2 抗体 (ABIN3032647)

抗原

See all SUMO2 抗体
SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

适用

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人, 大鼠

宿主

  • 83
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小鼠

克隆类型

  • 84
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单克隆

标记

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This SUMO2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

973CT8-1-1
  • 交叉反应 (详细)

    Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate

    纯化方法

    Purified

    免疫原

    Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.

    亚型

    IgG2b
  • 应用备注

    Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SUMO-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

    别名

    SUMO-2

    背景

    Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

    UniProt

    P61956

    途径

    Methionine Biosynthetic Process
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