SIRT6 抗体 (AA 276-305)
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北京 101111
Quick Overview for SIRT6 抗体 (AA 276-305) (ABIN3032596)
抗原
See all SIRT6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 276-305
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 276-305 from the human protein was used as the immunogen for this SIRT6 antibody.
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亚型
- Ig Fraction
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anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 适用: 人, 小鼠, 大鼠, 猴 WB, IP, IF 宿主: 小鼠 Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 适用: 人, 大鼠, 犬, Cow WB, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 35-274) antibodySIRT6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1135 unconjugated Recombinant Antibody
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 适用: 人, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
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应用备注
- Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SIRT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SIRT6 (Sirtuin 6 (SIRT6))
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别名
- SIRT6
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背景
- NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity).
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UniProt
- Q8N6T7
抗原
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