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SIRT5 抗体 (AA 263-292)

This anti-SIRT5 antibody is a 兔 多克隆 antibody detecting SIRT5 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN3032595
发货至: 中国

Quick Overview for SIRT5 抗体 (AA 263-292) (ABIN3032595)

抗原

See all SIRT5 抗体
SIRT5 (Sirtuin 5 (SIRT5))

适用

  • 92
  • 52
  • 32
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2

宿主

  • 90
  • 12
  • 2
  • 2

克隆类型

  • 85
  • 21
多克隆

标记

  • 51
  • 17
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT5 antibody is un-conjugated

应用范围

  • 83
  • 38
  • 34
  • 20
  • 13
  • 13
  • 12
  • 10
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-292

    纯化方法

    Purified

    免疫原

    A portion of amino acids 263-292 from the human protein was used as the immunogen for this SIRT5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the SIRT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SIRT5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SIRT5 (Sirtuin 5 (SIRT5))

    别名

    SIRT5

    背景

    SIRT5 is an NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX. [UniProt]

    UniProt

    Q9NXA8

    途径

    SARS-CoV-2 Protein Interactome
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