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S100B 抗体

This anti-S100B antibody is a 兔 多克隆 antibody detecting S100B in WB, IHC, FACS 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN3032516
发货至: 中国

Quick Overview for S100B 抗体 (ABIN3032516)

抗原

See all S100B 抗体
S100B (S100 Calcium Binding Protein B (S100B))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This S100B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
  • 交叉反应 (详细)

    Expected species reactivity: Rabbit

    纯化方法

    Antigen affinity purified

    免疫原

    This S100B antibody was produced from rabbits immunized with S100B recombinant protein.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the S100B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the S100B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    S100B (S100 Calcium Binding Protein B (S100B))

    别名

    S100B

    背景

    S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

    UniProt

    P04271

    途径

    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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